Dr. Gillett and Nurse Practitioner James O'Hara discuss Biotin and whether it's worth it. 

00:00 Intro

02:31 How did James find out he had a deficiency

05:09 Why supplement with Biotin?

08:09 Things not to eat if you want to get enough biotin 

09:13 How does this rank among other metabolic diseases 

12:17 What does it mean by enzymatic activity?

13:27 Carnitine depletion

14:28 James O’Haras Labs 

19:50 Outro 

Studies/References 

► https://www.hsph.harvard.edu/nutritionsource/biotin-vitamin-b7/

► https://www.nature.com/articles/gim20116

► https://examine.com/supplements/biotin/

► biotin supplement market 

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Dr. Gillett and James O'Hara NP, review an anti-aging protocol.

00:00 Intro

01:21 When to take HCG for fertility?

03:04 What was your optimized Free T before TRT?

08:00 Does L-Carnitine Raise TMAO

10:38 Total testosterone with vericocele

11:48 Do the providers recommend SubQ

13:37 Why are we calling Dutasteride anabolic?

14:37 Adverse effects of 5 alpha-reductase inhibitors.

16:50 what would a constantly high SHBG mean?

18:22 Testosterone and Dutasteride Question

21:07 How high is our endogenous testosterone?

21:42 What does Kyle mean when he refers to a traffic jam?

24:18 Should you be scared of creatine and hair loss?

24:49 Are we available in California?

25:18 Kyle’s favorite canned sardines?

25:42 Will creatine help post op surgery?

26:18 Why is James on TRT?

30:03 Are we concerned with PFS?

32:11 Turkesteron/Ecdysteroids and Tongkat/Fadogia

35:15 Thoughts on compounded test creams?

36:54 Thoughts on Varicoceles

39:52 Does L-Carnatine have an impact on hair?

40:43 Does gorilla minds sigma impact Dutasteride/Finasteride?

45:12 Lab work question

47:13 How can I get 12.5” guns

48:14 Should I switch to Dutasteride?

49:33 Proviron

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Dr. Gillett and James O'Hara NP, review an anti-aging protocol. 

00:00 - Introduction

02:18 - Bryan Johnson's personalized hair formula

09:11 - Bryan Johnson's daily routine

19:18 - Xeomin facial injections

21:48 - Vampire facial treatment

30:00 - Recap

31:44 - Outro

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Dr. Gillett and Nurse Practitioner James O'Hara Discuss their anabolic stack.

00:00 - Intro

01:15 - James Stack Creatine

03:40 - Omega 3s

05:33 - Vitamin D3

07:57 - Testosterone

9:29 - Anabolic potential of Dutasteride

11:43 - Kyle’s Stack

12:36 - Creatine

14:07 - Taurine and beta alanine

16:04 - l-Carnitine

19:39 - Omegas

21:21 - Testosterone

24:50 - How much of a difference will all these make?

28:26 - Outro

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Dr. Gillett and Nurse Practitioner James O'Hara Discuss their hair protocols.

00:00 Intro

02:59 Kyle’s regimen

07:22 Hair Care Stack for Non-Fertility

11:32 Stimulant for Hair Growth

12:32 Micro Trauma Management

13:58 Enhancing Blood Circulation

15:09 Hair Care Stack for Fertility

19:05 James' Daily Routine

19:40 Managing Androgen Levels

24:54 Addressing Side Effects

26:52 Use of Ketoconazole

28:18 Stimulant for Hair Growth

32:36 Platelet-Rich Plasma Therapy for Scalp

37:14 Botulinum Toxin Treatment

38:50 Techniques for Pain Management during Microneedling

41:23 Outro

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Dr. Gillett and Nurse Practitioner James O'Hara discuss HSV.

00:00 Intro

01:27 3 types of infection

02:50 HSV 1

10:47 LabCorp Code for testing

11:50 3 reels

13:05 How to decrease risk

16:44 Unclear chart

18:23 Mycoplasma genitalium

22:14 Virgins with HSV 2

24:16 Outro

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Dr. Gillett and Nurse Practitioner James O'Hara answer a variety of different questions from our viewers.

00:00 Intro

00:31 How much Sun exposure is too much?

03:11 What’s helped patients with PFS the most?

05:48 Does Dutasteride affect facial hair

07:49 Does DHEA convert to Estradiol?

08:56 How much tadalafil is too much?

12:20 Does Fadogia affect testicular size?

13:49 Why are doctors prescribing Ketamine?

16:52 Does Creatine affect Finasteride?

18:11 Does activating MTOR help with depression?

21:25 Frequency of topical Dutasteride?

23:45 Trusting research data

24:33 Do you have to refrigerate Omega-3s?

27:17 Does Mesothearpy only have a localized effect?

30:02 Does Finasteride affect OCD?

31:25 Outro

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Dr. Gillett and Nurse Practitioner James O'Hara answer a wide variety of questions from the comment section and Instagram. 

00:00 Intro

00:25 How to avoid sensitivity issues with Dutasteride

03:28 Is there a safe medication or supplement to loose fat

05:25 Does Natesto suppress HPTA?

07:45 Cheaper GLP1 

09:36 Do we prefer brand name medication?

12:57 CAG Repeat question from the UK

15:34 Different Forms of DHEA

19:32 Does Red Yeast rice compare to statins? 

21:09 reason for .5mg of Dutasteride

23:08 Topical BPC-157

24:38 Sperm count after discontinuing Dutasteride

26:54 How to switch from daily Finasteride to Dutasteride 

30:39 Sugar Black market

32:13 Fish oil and TRT

33:54 Carnivore diet and plaque 

36:45 GLP1 and Thyroid Cancer 

40:17 Finasteride and Marijuana

40:40 How much sun exposure is too much? 

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Dr. Gillett and Nurse Practitioner James O'Hara discuss why bears don't get atherosclerosis, a bear who became a cigarette-smoking bear drinking war hero, and much more!

00:00 Intro

00:58 Tweet about bears

02:53 Unveiling Wontek, the bear with intriguing habits of smoking and drinking

05:11 Bears resistance to arteriosclerosis

12:30 Optimal protein intake for bears

13:37 Delving into the science of white, beige, and brown adipose tissue

22:19 Outro

Studies/References

► https://www.nejm.org/doi/full/10.1056/NEJMoa0808718

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Dr. Gillett and Nurse Practitioner James O'Hara discuss Dementia and Dementia reversal.

00:00 Intro

01:42 CrossFit 

03:15 Understanding Dementia

07:06 Dementia Prevention Toolkit

30:42 Hormone Replacement Therapy (HRT) and Dementia

41:13 Desmosterol 

45:10 Marketing Approaches for Dementia Reversal

58:01 Additional Considerations

01:08:36 The Landscape of Dementia Reversal

01:20:00 Outro

Studies/References 

► https://doi.org/10.1002/alz.12529

► https://journals.sagepub.com/doi/10.1177/0891988720933351

► https://doi.org/10.3389/fnut.2022.723555

► https://content.iospress.com/articles/journal-of-alzheimers-disease/jad215707

► https://www.sciencedirect.com/science/article/pii/S156816372200277X#tbl0010

► https://www.tandfonline.com/doi/full/10.1080/13697137.2020.1804545

► https://www.sciencedirect.com/science/article/abs/pii/S0306453018311478

► https://pubmed.ncbi.nlm.nih.gov/31738372/

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Dr. Gillett and Nurse Practitioner James O'Hara discuss CAG Repeats.

00:00 Intro

0:24 Old-School to New-School Perspectives

2:49 Unpacking Key Discoveries from the Initial Research Endeavor

6:01 How SARMS Influence Androgen Receptor Functionality

7:52 DHEA-Testosterone-DHT

11:42 Relationship Between CAG Repeats and Sexual Function

19:14 How CAG Repeats Impact Reproductive Health

19:30 Link Between CAG Repeats and Prostate Health

21:56 Relationship Between CAG Repeats and Cardiovascular Health

24:02 How CAG Repeats Affect Bone Density

28:26 Role of CAG Repeats in the Body Composition of Russian Athletes

35:03 Outro

36:30 Out Takes

Studies/References

► https://pubmed.ncbi.nlm.nih.gov/2723028/

► https://www.medrxiv.org/content/10.1101/2023.02.08.23285647v1

► https://researchonline.ljmu.ac.uk/id/eprint/15126/3/Androgen receptor gene microsatellite polymorphism is associated with muscle mass and strength in bodybuilders and power athlete status .pdf

► https://pubmed.ncbi.nlm.nih.gov/20133446/

►https://www.researchgate.net/publication/281575383_Influence_of_CAG_Repeat_Polymorphism_on_the_Targets_of_Testosterone_Action

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Dr. Gillett and Nurse Practitioner James O'Hara discuss GLP1s specifically Tirzepatide

00:00 intro

02:56 Semaglutide and Trizepatide trial

03:56 Are compounded GLP1 safe?

08:35 Lifestyle change intervention

17:06 Comments from the authors on why some dropped out

18:43 Why some people struggle to stay in good shape

22:45 Price of Semaglutide

24:35 Outro

Studies/References

► http://medspa.com/

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Dr. Gillett and Nurse Practitioner James O'Hara discuss the 75 hard challenge.

00:00 Intro

00:59 5 critical rules

16:41 Is 75 hard healthy?

17:53 75 soft

20:39 Outro

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Dr. Gillett and Nurse Practitioner James O'Hara discuss lean mass hyper responders.

00:00 Intro

1:28 Potential Risks

6:31 Unmodifiable Factors

10:43 Effects of Smokeless Tobacco

14:10 Guidelines by USPSTF

27:10 A Comparison with ACS

28:50 Prostate Cancer and PSAs

32:19 Innovations in Cancer Testing

42:02 The Link Between Obesity and Cancer Risk

43:43 Increased Risk with GLP1s

48:36 Comprehensive Analysis of Full Body MRI's

53:24 Outro

Studies/References

► https://journals.humankinetics.com/view/journals/ijsnem/29/5/article-p466.xml

► https://www.frontiersin.org/articles/10.3389/fphys.2023.1195702/full

► https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324611/

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Dr. Gillett and Nurse Practitioner James O'Hara discuss different cancer risks, new cancer detection methods, and possible preventions.

00:00 Intro

1:28 Potential Risks

6:31 Unmodifiable Factors

10:43 Impact of Smokeless Tobacco

14:10 Guidelines by USPSTF

27:10 ACS Comparison

28:50 Prostate Cancer and PSAs

32:19 Innovative Cancer Testing Methods

42:02 The Connection Between Obesity and Cancer Risk

43:43 Elevated Risk with GLP1s

48:36 Comprehensive Full Body MRI

53:24 Outro

Studies/References

► https://onlinelibrary.wiley.com/doi/full/10.1111/jop.12810

► https://doi.org/10.1016/S1470-2045(08)70173-6

► https://www.invitae.com/us/providers/test-catalog/test-01101

► https://www.invitae.com/us/providers/test-catalog/test-01102

► https://amp.cancer.org/cancer/screening/american-cancer-society-guidelines-for-the-early-detection-of-cancer.html

► https://grail.com/press-releases/final-results-from-pathfinder-study-of-grails-multi-cancer-early-detection-blood-test-published-in-the-lancet/

► https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01700-2/fulltext

► https://www.thelancet.com/cms/attachment/3fa623ed-8b06-4904-83e9-16118575121e/gr2.gif

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Dr. Gillett and Nurse Practitioner James O'Hara discuss sexual health, exploring a spectrum of strategies to optimize and enhance.

00:00 Intro

01:43 Exploring Hypoactive Sexual Desire Disorder and the Sexual Function Triad

05:02 Unveiling the Reel of PDE5 Inhibitors

05:38 Navigating the Partner's Choice in Sexual Health

13:04 Understanding the Role of Androgens in Men's Sexual Function

19:27 Shedding Light on Testosterone's Impact on Women's Sexual Health

25:40 Examining the Long-Term Safety of Sexual Health Interventions

28:33 Unpacking Vyleesi: A Closer Look at its Mechanism

32:56 Trazodone and PT-141: Exploring Alternative Approaches

34:24 Addyi: Assessing its Role in Enhancing Female Libido

37:30 Bupropion: An Overview of its Impact on Sexual Function

41:43 Oxytocin and Apomorphine: Investigating Novel Approaches

47:21 Addressing Anorgasmia in the Spectrum of Sexual Health

50:14 Priapism: Understanding and Managing Persistent Erections

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53:28 Outro

Studies/References

► https://pubmed.ncbi.nlm.nih.gov/18312284/

► https://pubmed.ncbi.nlm.nih.gov/26797204/

► https://pubmed.ncbi.nlm.nih.gov/37589949/

► https://www.liebertpub.com/doi/full/10.1089/andro.2021.0033

► https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668626/

► https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/486664

► https://sci-hub.se/https://pubmed.ncbi.nlm.nih.gov/19108962/

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► https://gilletthealth.com/order-lab-panels/

For information on the Gillett Health clinic, lab panels, and health coaching:

► https://GillettHealth.com

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► https://instagram.com/kylegillettmd

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► https://Instagram.com/jamesoharanp

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► https://gorillamind.com/

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#podcast #optimization #libido #hormones #libido #gilletthealth

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Nurse Practitioner James O'Hara interviews David DeMesquita, an Olympia Coach and specialist in gut health/hormones.

Davids Links:

► https://www.instagram.com/dynamite_d/?hl=en

► https://www.youtube.com/@DavidDeMesquita/videos

For High-quality labs:

► https://gilletthealth.com/order-lab-panels/

For information on the Gillett Health clinic, lab panels, and health coaching:

► https://GillettHealth.com

Follow Gillett Health for more content from James and Kyle

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► https://www.tiktok.com/@gilletthealth

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► https://instagram.com/kylegillettmd

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► https://Instagram.com/jamesoharanp

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► https://gorillamind.com/

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►https://www.thorne.com/u/GillettHealth

#podcast #interview #bodybuilding #olympia #guthealth #hormones #gilletthealth

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Dr. Gillett and Nurse Practitioner James O'Hara delve into the reasons why withholding the publication of studies can be detrimental.

00:00 Intro

01:05 Undisclosed Human Study

07:07 Rapamycin and Ketamine Combination

15:50 Lifespan Impact: SIRT2 Transgenic Over-expression in Mice

18:23 Collaborative FDA Letter Addressing Obesity

21:36 Advocating for the Publication of Surprising Findings

28:32 Insights from Dr. Gillett's Surgical Experience

29:34 Conclusion

Studies/References

► https://clinicaltrials.gov/study/NCT03190785#publications

► https://pubmed.ncbi.nlm.nih.gov/32092760/

► https://onlinelibrary.wiley.com/doi/full/10.1111/acel.14027

► https://acsess.onlinelibrary.wiley.com/doi/full/10.2134/ael2015.10.0007

► https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.15370

For High-quality labs:

► https://gilletthealth.com/order-lab-panels/

For information on the Gillett Health clinic, lab panels, and health coaching:

► https://GillettHealth.com

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Follow Kyle Gillett, MD

► https://instagram.com/kylegillettmd

Follow James O’Hara, NP

► https://Instagram.com/jamesoharanp

For 10% off Gorilla Mind products including SIGMA: Use code “GH10”

► https://gorillamind.com/

For discounts on high-quality supplements

►https://www.thorne.com/u/GillettHealth

#podcast #study #discussion #science #gilletthealth

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Dr. Gillett and Nurse Practitioner James O'Hara delve into a conversation addressing the potential risks associated with omega-3 fatty acids.

00:00 Introduction

00:12 Emerging Risks Associated with Omega Fatty Acids

5:41 Synthesizing Insights from Four Significant Randomized Trials

16:00 Insights from Animal and Canine Studies

18:51 Examination of a DHA-Specific Trial

20:13 Addressing the Adequacy of a 500mg EPA Dosage

22:39 Exploring the Field of Nutrigenomics

24:57 Findings from a Cod Liver Oil Study

25:53 Investigating Blood Viscosity Concerns

27:13 Focusing on DHA Exclusive Trials

30:10 Unraveling the Link between Omega Fatty Acids and Gum Recession

30:43 Contrasting DHA versus EPA

31:41 Impact of Oxidized Fish Oil

37:54 Closing Thoughts and Outro

Studies/References

► https://www.jacc.org/doi/epdf/10.1016/j.jacc.2023.05.024

► https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.052209

► https://jamanetwork.com/journals/jama/fullarticle/2773120

► https://pubmed.ncbi.nlm.nih.gov/30415628/

► https://www.nejm.org/doi/pdf/10.1056/NEJMoa1811403?articleTools=true

► https://www.acc.org/clinical-topics/arrhythmias-and-clinical-ep/~/media/67142EC297834666B0CF741690027D9D.pdf

► https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.107.712984

► https://www.jstage.jst.go.jp/article/circj/86/5/86_CJ-21-0615/_pdf

► https://www.ahajournals.org/doi/pdf/10.1161/CIRCEP.112.971515

► https://pubmed.ncbi.nlm.nih.gov/2694923/

► https://pubmed.ncbi.nlm.nih.gov/18779276/

► https://pubmed.ncbi.nlm.nih.gov/17490962/

► https://pubmed.ncbi.nlm.nih.gov/2685599

► https://pubmed.ncbi.nlm.nih.gov/12145002/

► https://pubmed.ncbi.nlm.nih.gov/18555744/

► https://pubmed.ncbi.nlm.nih.gov/24970858/

► https://pubmed.ncbi.nlm.nih.gov/29846653/

► https://www.deepdyve.com/lp/wiley/effect-of-packaging-and-encapsulation-on-the-oxidative-and-sensory-ElE1I6yjXd?key=dd_plugin&utm_campaign=pluginGoogleScholar&utm_source=pluginGoogleScholar&utm_medium=plugin

► https://doi.org/10.1080/19390211.2023.2252064

For High-quality labs:

► https://gilletthealth.com/order-lab-panels/

For information on the Gillett Health clinic, lab panels, and health coaching:

► https://GillettHealth.com

Follow Gillett Health for more content from James and Kyle

► https://instagram.com/gilletthealth

► https://www.tiktok.com/@gilletthealth

► https://twitter.com/gilletthealth

► https://www.facebook.com/gilletthealth

Follow Kyle Gillett, MD

► https://instagram.com/kylegillettmd

Follow James O’Hara, NP

► https://Instagram.com/jamesoharanp

For 10% off Gorilla Mind products including SIGMA: Use code “GH10”

► https://gorillamind.com/

For discounts on high-quality supplements

►https://www.thorne.com/u/GillettHealth

#podcast #omega #omega3 #cells #health #gilletthealth

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Dr. Gillett and Nurse Practitioner James O'Hara Answer your questions about Finasteride and Dutasteride.

00:23 Commencement of AMA (Initial Segment)

02:27 Dosage Considerations

05:13 Exploring Topical Dutasteride and its Half-life

08:50 Front-loading Dutasteride: Is it Necessary?

10:27 Contemplating the Switch from Finasteride to Dutasteride (Derek Reel)

14:21 Assessing the Comparative Side Effects of Oral Dutasteride

15:26 Examining Dutasteride's Potency in Inhibiting Type 2

18:46 Manipulating Net Androgens for Individuals on TRT

21:07 Unraveling the Mystery of Reversing Grey Hair

22:55 Understanding the Challenge of Detecting Systemic Absorption in Topical Dutasteride

24:40 Strategies for Managing Male Pattern Baldness

25:53 Exploring Hair Loss Treatments Minus Sexual Side Effects

27:02 Addressing a Cluster of Questions

30:52 Gillett Health's Insights into Finasteride's Side Effects

31:37 Optimal Dosing Protocols

32:30 Navigating Finasteride and Saw Palmetto Interactions

32:59 Neurological Side Effects: Is Dutasteride a Safer Option?

35:41 Crafting a Recommended Hair Loss Protocol

37:29 Establishing Protocols for Prostate Cancer Prevention

38:40 Continual Hair Loss Eight Months In: What to Do?

39:05 Managing Post-Finasteride Syndrome (PFS)

41:50 Alternative Hair Growth Treatments for Women

43:06 Updates on Antiandrogen Drugs

43:44 Gillett Health's Offerings: How We Can Assist You

For High-quality labs:

► https://gilletthealth.com/order-lab-panels/

For information on the Gillett Health clinic, lab panels, and health coaching:

► https://GillettHealth.com

Follow Gillett Health for more content from James and Kyle

► https://instagram.com/gilletthealth

► https://www.tiktok.com/@gilletthealth

► https://twitter.com/gilletthealth

► https://www.facebook.com/gilletthealth

Follow Kyle Gillett, MD

► https://instagram.com/kylegillettmd

Follow James O’Hara, NP

► https://Instagram.com/jamesoharanp

For 10% off Gorilla Mind products including SIGMA: Use code “GH10”

► https://gorillamind.com/

For discounts on high-quality supplements

►https://www.thorne.com/u/GillettHealth

#podcast #aşk #finasteride #hairloss #hormones #gilletthealth

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