Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges

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“What’s the best way to screen?” This episode breaks down the pros, limitations, and follow-up needs of FIT, Cologuard, CT colonography, and colonoscopy to help you choose the right screening option for your patients. Also learn practical colonoscopy surveillance intervals based on polyp size, number, and pathology. 🔹Sponsor: Search “<a href="https://www.coreimpodcast.com/Pharmacy5" rel="nofollow">Amazon Pharmacy</a> Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day).<a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow"> </a><a href="https://www.coreimpodcast.com/Pharmacy5" rel="nofollow">Learn more here!</a> 🔹<a href="https://www.coreimpodcast.com/2026/10/07/crc-screening-part-2" rel="nofollow">Transcript and Show Notes</a>01:24 | Screening Options Besides Colonoscopy11:22 | How FIT, FIT-DNA, and CT colonography differ and when each makes sense.12:52 | Colonoscopy and Frequency19:29 | How adenoma number, size, and histology guide surveillance intervals.  Tags: Core IM, Internal Medicine, Colorectal Cancer Screening, Gastroenterology, Cancer Screening  Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#220 CRC Screening Nuances: 5 Pearls Segment Part 2

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“The triglycerides are high. Now what?” This episode breaks down a practical approach to elevated TGs, from knowing when to check ApoB or non-HDL-C to choosing lifestyle changes, lipid-lowering medications, and when to suspect an underlying genetic disorder.  🔹<a href="https://www.coreimpodcast.com/2026/09/29/updates-in-triglycerides/" rel="nofollow">Transcript and Show Notes</a>02:17 | Check a non-HDL-C or ApoB if TGs are ≥150 mg/dL 07:18 | Address waist circumference and lifestyle before meds for high TGs10:52 | Dr. Watson’s 3-day carbohydrate responsiveness trial 17:07 | Order a fasting or nonfasting lipid panel?19:00 | When do you reach for TG-lowering medications? 25:26 | Familial chylomicronemia syndrome (FCS) Tags: CoreIM, Medical Education, Hypertriglyceridemia, ACC AHA lipid guidelines, lipid guidelines 2026, cardiovascular risk  Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#219 Updates in Triglycerides

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“Too young for colon cancer.” This episode unpacks the red flags of early-onset CRC, from blood in the stool and iron deficiency anemia to persistent abdominal pain and changes in bowel habits, and offers practical pearls for closing the clinical loop. Also learn why a “negative” family history may need a yearly refresh. 🔹Sponsor: Search “<a href="https://www.coreimpodcast.com/Pharmacy5" rel="nofollow">Amazon Pharmacy</a> Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day).<a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow"> </a><a href="https://www.coreimpodcast.com/Pharmacy5" rel="nofollow">Learn more here!</a> 🔹<a href="https://www.coreimpodcast.com/2026/09/23/early-onset-crc-5-pearls-segment-part-1/" rel="nofollow">Transcript and Show Notes</a> 01:45 | Colorectal cancer rising in younger adults 06:42 | Why screening starts at age 4508:15 | What may be driving early-onset colorectal cancer 13:37| Key takeaways: symptoms, follow-up, and family history  Tags: Colorectal Cancer Screening, Internal Medicine, Gastroenterology, Cancer Screening, Oncology Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#218 Early-Onset CRC: 5 Pearls Segment Part 1

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“It didn’t work.” This episode breaks down practical treatment options (dosing options for naltrexone, acamprosate, topiramate, gabapentin) and counseling pearls to help you meet patients where they are and support their recovery. Also discover blind spots in detox and rehab centers.🔹<a href="https://www.coreimpodcast.com/2026/09/16/treatment-for-alcohol-use-disorder-5-pearls-segment" rel="nofollow">Transcript and Show Notes</a>🔹 Explore ACP’s Substance Use Disorder Education Hub for videos and an AI-powered patient simulation to practice alcohol-use conversations: <a href="https://www.coreimpodcast.com/SUDhub" rel="nofollow">https://www.coreimpodcast.com/SUDhub</a><a href="https://www.coreimpodcast.com/ASAMVideos" rel="nofollow">Alcohol Use and Chronic Health Conditions Mini Video Series</a>01:55 | #1: Naltrexone12:06 | #2 Acamprosate16:15 | #3: Topiramate21:12 | #4: Other meds29:31 | #5: Detox and rehab blind spots  Tags: CoreIM, Medical Education, Addiction Medicine, Alcohol Withdrawal, Addiction Treatment, GLP-1, pharmacology Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#217 Treatment for Alcohol Use Disorder: 5 Pearls Segment

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Have you ever lost a patient and found yourself thinking about them long after the shift ended? This episode explores the grief clinicians can carry after a patient dies, including the losses that aren’t always obvious. We also discuss ways to work through that grief, recognize when it becomes complicated, and lean on your team for support.   🔹<a href="https://www.coreimpodcast.com/2026/09/08/at-the-bedside-clinician-grief" rel="nofollow">Transcript and Shownotes</a>04:12 | What is Clinician Grief?10:02 | Types of Losses10:22 | Loss of a close relationship with a particular patient12:56 | Loss due to a professional&#39;s identification with the pain of family members13:56 | Loss of one&#39;s unmet goals and expectations and one&#39;s professional self-image and role18:47 | Loss related to one&#39;s personal system of beliefs and assumptions about life21:30 | Past unresolved losses or anticipated future losses23:29 | The death of the self25:44 | Coping Tags: CoreIM, Medical Education, Clinician Wellbeing, Burnout, Secondary Traumatic Stress, Complicated Grief, Coping With Grief, Medical humanities, medical ethics Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#216 Clinician Grief: At the Beside Segment

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How to choose between RUQ ultrasound, CT, HIDA, MRCP, EUS, and ERCP based on the clinical picture? When should you move from diagnostic imaging to therapeutic ERCP, and what should you know about sphincterotomy, stents, and stone removal? Plus, how to interpret bile duct dilation without jumping straight to obstruction? 🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a> 🔹Transcript and Shownotes 02:11 | Pearl 1: Gallbladder Problems Spectrum07:33 | Pearl 2: Choose Imaging Strategically: Start with RUQUS, Escalate as Needed14:34 | Pearl 3: Biliary Tree Diagnostics19:19 | Pearl 4: Invasives that are Diagnostic and Therapeutic27:06 | Pearl 5: Stenting in ERCP Tags: CoreIM, Internal Medicine, Medical Education, Gallstones, Cholecystitis, Biliary Disease, ERCP, Biliary Imaging Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#215 Gallbladder & Biliary Testing: 5 Pearls Segment

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Throwback: Should you really fluid-restrict every patient with SIADH? When can IV fluids make hyponatremia better or worse? Are salt tabs actually doing enough? And what can urine studies tell you before you start treatment? Join us for a practical, physiology-driven approach to hyponatremia management, from fluids and solutes to loop diuretics and identifying the underlying cause.  🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day). <a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow">Learn more here</a>. 🔹<a href="https://www.coreimpodcast.com/2022/08/03/hyponatremia-management-part-1-5-pearls-segment/" rel="nofollow">Transcript and Shownotes</a> 6:46 | Pearl 1: Key Principles15:13 | Pearl 2: Fluids in hyponatremia26: 03 | Pearl 3: Solutes in hyponatremia management35:49 | Pearl 4: Lasix in hyponatremia management40:05 | Pearl 5: Etiologies Tags: CoreIM, Internal Medicine, Medical Education, SIADH, Fluid Restriction, Nephrology, Hospital Medicine, Urine Osmolality Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#214 Hyponatremia Management: A Core IM Classic

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Why can lower-dose combinations be more effective and better tolerated than maximizing one medication? How to troubleshoot common challenges such as amlodipine edema, gout, electrolyte abnormalities, and the patient who says they cannot tolerate anything? Why ACT (ARBs, Calcium Channel Blockers, Thiazides) is the preferred first-line framework, and how to personalize medication choices based on comorbidities and side effects. 🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a>  🔹<a href="https://www.coreimpodcast.com/2026/07/28/hypertension-cases-3-first-line-meds/" rel="nofollow">Transcript and Shownotes</a> 03:00 | Diagnosing Hypertension 04:10 | When to Start Combination Therapy Instead of Monotherapy 07:00 | Choosing First-Line Therapy Using the ACT Framework 13:23 | Why ARBs Are Often Preferred Over ACE Inhibitors 16:02 | Choosing the Right ARB: Candesartan vs Losartan 18:39 | Comparing Potency &amp; Duration Across First-Line Antihypertensives 20:54 | Amlodipine Edema: Why It Happens and How to Fix It 23:54 | Thiazides: Practical Tips, Electrolyte Problems &amp; Class-Killer Side Effects 29:33 | Managing Patients Who &#39;Can&#39;t Tolerate&#39; Blood Pressure Medications  Tags: Hypertension Management, High Blood Pressure, Primary Care, Internal Medicine, Core IM Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#213 Hypertension First-Line Medications Troubleshooting | Bread & Butter Series

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Learn from primary care docs what has been practiced and changed from the 2026 ACC/AHA Lipid Guidelines! Learn how the new CPR framework (Calculate, Personalize, Reclassify) and PREVENT risk calculator change statin decisions, why LDL targets are back, and when to use Lp(a), ApoB, and coronary artery calcium (CAC) testing. Discover updated risk-enhancing factors, expanded indications for non-statin therapies, and practical strategies to personalize lipid management for both primary and secondary 🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day). <a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow">Learn more here</a>. 🔹<a href="https://www.coreimpodcast.com/2026/07/15/top-10-highlight%E2%80%A6lipid-guidelines/" rel="nofollow">Transcript and Shownotes:  </a>01:17 | Highlight #1 &amp; #2: CPR and PREVENT Score03:14 | Highlight #3: Updated ASCVD Risk Categories Using the PREVENT Score05:30 | Highlight #4: LDL Targets Are Back07:20 | Highlight #5: High-Risk Conditions That Bypass the PREVENT Score08:41 | Highlight #6: Lp(a) Screening for Everyone11:51 | Highlight #7: When to Use ApoB Testing13:16 | Highlight #8: Reproductive Risk Factors15:29 | Highlight #9: Using CAC to Guide Statin Therapy19:09 | Highlight #10: Non-Statin Therapies Tags: CoreIM, Internal Medicine, Medical Education, Cholesterol, Statins, LDL, ASCVD, Preventive Cardiology, LpA, ApoB, CAC, ACC2026, Cardiology, PrimaryCare  Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#212 Top 10 Highlights of the New Lipid Guidelines

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MASLD affects nearly one in three adults worldwide, yet many patients remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening? When is a FIB-4 enough, and when should we move to elastography or hepatology referral? And are we finally entering an era where we can meaningfully treat MASH?In this Beyond Journal Club episode, we unpack the evolving language of steatotic liver disease and take a close look at two major trials: MAESTRO-NASH studying resmetirom, the first FDA-approved liver-directed therapy for MASH, and ESSENCE, evaluating semaglutide in biopsy-confirmed disease.Along the way, we explore what these biopsy-based histologic endpoints really mean, why placebo responses were surprisingly high, and whether improvements in steatohepatitis and fibrosis will ultimately translate into better clinical outcomes for patients.This episode is for clinicians trying to understand where the field is headed, which patients deserve closer attention, and how metabolic liver disease is increasingly becoming part of everyday primary care and hospital medicine. 🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a>  🔹<a href="https://www.coreimpodcast.com/2026/06/29/breaking-down-masld-vs-mash-and-maestro-nash-essence-trials-beyond-journal-club-segment/" rel="nofollow">Transcript and Shownotes</a>:  01:57 | Understanding MASLD as a Systemic Disease 05:45 | MASLD vs MASH vs Met-ALD: Spectrum Steatotic Liver Disease 08:55 | How to Screen for Fibrosis (FIB-4 &amp; FibroScan) 16:15 | Lifestyle Treatment &amp; Weight Loss Targets 19:00 | ESSENCE Trial: Semaglutide for MASH 21:58 | MAESTRO-NASH Trial: Resmetirom 27:27 | Future Treatments for MASH 30:51 | Key Takeaways for Clinicians  Tags: CoreIM, Internal Medicine, Medical Education, Hepatology, Fatty Liver Disease, Metabolic Dysfunction Associated Steatohepatitis, Nonalcoholic Fatty Liver Disease, Liver Fibrosis Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#211  Breaking Down MASLD vs. MASH and the MAESTRO-NASH & ESSENCE Trials: Beyond Journal Club Segment

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What blood pressure should we target in patients on hemodialysis? Why volume control remains the foundation of treatment? How blood pressure targets differ from the general population. Learn practical pearls on medication timing around dialysis, drug dialyzability, antihypertensive selection, and strategies to prevent intradialytic complications while optimizing long-term outcomes.  🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day). <a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow">Learn more here</a>.  <a href="https://www.coreimpodcast.com/2026/06/17/htn-in-esrd-5-pearls-segment/" rel="nofollow">🔹Transcript and Shownotes:  </a>02: 19 | Pearl 1: Blood Pressure Targets 09: 40 | Pearl 2: Timing Medications and Dialyzability 15: 31 | Pearl 3 - Pharmacologic Management Nuances in Dialysis Patients 22: 57 | Putting It All Together: The Medication Hierarchy  Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, ESRD, End-Stage Kidney Disease, Hypertension, Kidney Health, Dry Weight, Volume Overload Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#210 HTN in Dialysis: 5 Pearls Segment

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Why is fluid management the most important part of dialysis care? This episode explores the fundamentals of hemodialysis, why ESKD patients have unique physiology, and how volume overload, not just hypertension, drives many complications. Learn practical pearls on dry weight, sodium restriction, diuretics, and the strategies that can reduce hospitalizations and improve patient outcomes.  🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a>  🔹<a href="https://www.coreimpodcast.com/2026/06/10/fluid-management-in-eskd-patients-on-hemodialysis-5-pearls-segment/" rel="nofollow">Transcript and Shownotes</a>:  02:49 | Pearl 1: Foundations of Dialysis09:21 | Pearl 2: Distinct Physiology11:42 | Pearl 3: Why is fluid management so important?19:43 | Pearl 4: Fluid Management Pro-tips25:31 | Pearl 5: Diuretics in Patients with Residual Kidney Function Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, Dialysis, End-stage kidney disease, Hypertension, Kidney Health, Dry Weight, Volume Overload Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#209 Dialysis and Fluid Management: 5 Pearls Segment

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Can AI manage post-op atrial fibrillation or does medicine still require human judgment? Using post-op AFib as a case study, we explore where algorithms help, where evidence falls short, and why clinical context still matters. When evidence is incomplete, and every patient is different, can AI truly practice medicine or only assist the clinicians who do? This episode explores the space between algorithms, uncertainty, and human judgment in modern medical care.  🔹Sponsor: Search “Amazon Pharmacy Nationwide Home Delivery&#34; in your EHR to get home delivery (often same-day). <a href="https://www.coreimpodcast.com/Amazonpharmacy" rel="nofollow">Learn more here</a>. 🔹<a href="https://www.coreimpodcast.com/2026/05/27/ai-vs-human-with-post-op-afib-bread-butter-series/" rel="nofollow">Transcript and Shownotes</a>:  02:51 | Broad workup for reversible causes and other etiologies of AFib that may occur post-op05:10 | Considerations for management of post-op atrial fibrillation13:00 | Stroke risk in atrial fibrillation20:49 | Outpatient management of atrial fibrillation 25:54 | The role of AI in medical decision-making Tags: CoreIM, Internal Medicine, Medical Education, Atrial Fibrillation, Cardiology, Open Evidence Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#208 AI vs. Human with Post-Op AFib: Bread & Butter Series

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We start with a gripping story of seizures and use it as a jumping-off point to unpack practical pearls for in-flight emergencies. Along the way: what’s actually in the emergency medical kit, when planes divert, how ground medical support works, altitude physiology, legal protections, and how to stay calm when medicine suddenly happens at 35,000 feet. By the end, you may still sweat a little…but hopefully less than before.🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a> 🔹<a href="https://www.coreimpodcast.com/2026/05/18/inflight-emergencies/" rel="nofollow">Transcript and Shownotes</a>:   04:40 | Emergency Medical Kit (EMK) Standard Contents08:50 | Role of Ground-Based Medical Support &amp; Flight Diversion Decision-Making19:35 | Interpreting Hypoxia at Altitude22:06 | In-Flight Liability23:35 | Common Chief Concerns &amp; Useful Additional Medications24:53 | How to Be Resourceful in an Austere Environment Tags: CoreIM, Internal Medicine, Medical Education, In-flight Care, Medical Emergencies, Clinical Reasoning, Seizure Management, Hypoxia, Airway Management, Cardiac Emergency, Syncope, Respiratory Distress Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#207 Is There a Doctor on Board? In-Flight Emergencies

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Can you distinguish benign eosinophilia from a sign of serious disease, and know exactly when to act at the bedside?In this high-yield episode, test your clinical reasoning as we tackle:<ul><li>When eosinophilia becomes dangerous and why it matters</li><li>How to distinguish if its from atopy vs. systemic disease</li><li>Which medications to stop (and which to watch)</li><li>How travel, diet, and exposure history shape your workup</li><li>When to suspect malignancy before giving steroids</li></ul> 🔹<a href="https://www.coreimpodcast.com/2026/04/28/eosinophilia-5-pearls-segment/" rel="nofollow">Transcript and Shownotes</a>: 02:34 | Why Do We Care About Eosinophilia? (Pearl 1)10:24 | Atopy and Eosinophilia (Pearl 2)18:57 | Drugs and Eosinophilia (Pearl 3)27:29 | ID and Eosinophilia (Pearl 4)33:54 | Pearl 5: Eosinophilia, Steroids, and Neoplasms (Pearl 5) Tags: CoreIM, Internal Medicine, Medical Education, Eosinophilia, Hypereosinophilia, Allergy Immunology, Hematology, Pulmonology, Parasitic Infections, Atopy Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#206 Eosinophilia: 5 Pearls Segment

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Is coffee helping or harming our patients’ hearts?In this Beyond Journal Club, we unpack the CRAVE trial and use it as a lens to answer a bigger question:How should clinicians interpret nutrition research, especially when it feels inconsistent or hard to trust?Listen for a concise, practical framework you can use the next time a patient asks about coffee, diet, or lifestyle. 🔹Sponsor: Oakstone CMEUse the code &#34;CORE25&#34; for 25% off: <a href="https://www.coreimpodcast.com/MKSAP" rel="nofollow">https://www.coreimpodcast.com/MKSAP</a> 🔹 <a href="https://www.coreimpodcast.com/2026/04/15/nutrition-coffee-bjc-nejm/" rel="nofollow">Transcript and Show notes</a>00:00 | Challenges of interpreting nutritional research.02:22 | Best practices for evaluating studies in nutrition. 12:35 | Delve into the CRAVE trial as an example of critically appraising nutritional investigations.26:41 | Applying this to clinical practice for your patients. Tags: IMCore, Internal Medicine, Medical Education, Epidemiology, Diet and Lifestyle Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group

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Why can these infections be tricky? How to diagnose osteomyelitis at the bedside? Do we always need IV vs oral antibiotics? And the best for last: Simple, practical wound care strategies for medical students, residents, and clinicians who want a clear, usable approach. .🔹Sponsor: <a href="https://www.coreimpodcast.com/DoxGPT" rel="nofollow">DoxGPT</a> by Doximity - an AI assistant built with practicing clinicians to deliver bottom-line clinical answers, chart summaries, secure calls, and faxing directly inside the Doximity app. See how fast it is and how easy to read at <a href="https://www.coreimpodcast.com/DoxGPT" rel="nofollow">DoxGPT.com</a> 🔹<a href="https://www.coreimpodcast.com/2026/04/01/diabetic-foot-infection/" rel="nofollow">Transcript and Shownotes</a>:02:15 | Pearl 1: Pathophysiology08:20 | Pearl 2: Diagnosis16:35 | Pearl 3: Treatment20:35 | Pearl 4: Antibiotics27:39 | Pearl 5: Wound Care Tags: CoreIM, Internal Medicine, Medical Education, Diabetic Foot Infections, Osteomyelitis, Foot Ulcer, Wound Care Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment

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A dialysis patient with a chronic cough: is it COPD, or are they still volume overloaded?A patient with AKI and hyperkalemia says they’re still peeing — does that rule out post-obstructive AKI?A patient arrives in the ED with uremic symptoms and a newly created AV fistula. Can you safely use it, or do you need to place a temporary dialysis catheter?And the classic inpatient dilemma: your heart failure patient looks better after diuresis, but the creatinine is rising. Is it time to stop, or should you keep going? 🔹Sponsor: Pain Management and Opioids Adaptive Learning Free Online Course by NEJM Group: <a href="https://cme-info.nejm.org/core-im/" rel="nofollow">https://cme-info.nejm.org/core-im/</a>See <a href="https://ajkdblog.org/category/nephmadness/" rel="nofollow">here</a> for Neph Madness details See <a href="https://ajkdblog.org/2026/03/01/nephmadness-2026-pocus-region/" rel="nofollow">here</a> for the POCUS region of NephMaddnessVOTE <a href="https://www.tourneytopia.com/AJKD/NephMadness/SubmitPicks/Picks.aspx" rel="nofollow">here</a> to build your bracket!🔹<a href="https://www.coreimpodcast.com/2026/03/23/pocus-for-aki-dialysis-real-cases-that-changed-management/" rel="nofollow">Transcript and Shownotes</a>: 00:52 | What is NephMadness?02:19 | Detecting post-renal obstruction in a patient who reported normal urination11:26 | POCUS for discharge or continue diurese 17:25 | Distinguishing COPD from volume overload in a dialysis patient using lung ultrasound23:55 | Assessing AV fistula maturity at the bedside to potentially avoid placing a temporary dialysis line Along the way, we discuss practical ways clinicians can use renal, lung, and venous ultrasound to clarify uncertain clinical situations and make faster decisions at the bedside. If you’ve ever paused on rounds, wondering “what should we do next?” in a patient with kidney disease, this episode explores how POCUS can help answer that question. Tags: CoreIM, Internal Medicine, Medical Education, Nephrology, AKI Management, POCUS Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#203 POCUS for AKI & Dialysis | Real Cases That Changed Management

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Most clinicians see dementia medications on the med rec, but many of us aren’t sure how much they actually help. In this episode we break down donepezil, memantine, and the new anti-amyloid drugs, and when to stop them.• Do cholinesterase inhibitors really work?• What should clinicians know about lecanemab and donanemab before referring patients?• How much benefit should we expect and for how long?• When should you deprescribe dementia medications? 🔹Sponsor: Caraway’s cookware set is a favorite for a reason.For 10% off, go to <a href="http://carawayhome.com/CoreIM" rel="nofollow">Carawayhome.com/CoreIM</a> or use code CoreIM at checkout. 🔹<a href="https://www.coreimpodcast.com/2026/03/12/dementia-part-2-gray-matters-segment/" rel="nofollow">Transcript and Shownotes</a>02:27 | Deep Dive 1: How do we deliver the news of a diagnosis of dementia?09:41 | Deep Dive 2: Prescribing medications for cognitive decline29:30 | Deep Dive 3: Patient-centered management for a patient with cognitive decline35:46 | Deep Dive 4: Planning for an uncertain future Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#202 Dementia Part 2: Gray Matters Segment

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Cognitive decline is tough for all parties. What are the high-yield questions to ask? What should you add to your one-liner? When do you stop using MOCA and try to clearly describe their functional status? Do all patients with cognitive decline need an MRI? 🔹Sponsor: <a href="https://www.coreimpodcast.com/DoxGPT" rel="nofollow">DoxGPT</a> by Doximity - an AI assistant built with practicing clinicians to deliver bottom-line clinical answers, chart summaries, secure calls, and faxing directly inside the Doximity app. See how fast it is and how easy to read at <a href="https://www.coreimpodcast.com/DoxGPT" rel="nofollow">DoxGPT.com</a> 🔹<a href="https://www.coreimpodcast.com/2026/02/25/dementia-part-1-gray-matters-segment" rel="nofollow">Transcript &amp; Shownotes</a>: 01:12 | Cognitive Concerns During a Routine Follow-Up03:41 | Deep Dive 1: How do you pivot when you recognize unexpected memory issues?15:08 | Deep Dive 2: What tools should we use to characterize and stage cognitive decline?31:09 | Deep Dive 3: How do we determine the etiology of cognitive decline? Tags: CoreIM, Internal Medicine, Medical Education, Cognitive Screening, primary care, nurse practitioner, physician assistant Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out ElevenReader and use my code PODCAST for a great deal: https://elevenreader.io Advertising Inquiries: <a href='https://redcircle.com/brands'>https://redcircle.com/brands</a> Privacy & Opt-Out: <a href='https://redcircle.com/privacy'>https://redcircle.com/privacy</a>

#201: Dementia Part 1: Gray Matters Segment

Core Internal Medicine via following series:
5 Pearls || Clinically relevant pearls 
Mind the Gap || Why do we do what we do?
Gray Matters || Management Reasoning
Hoofbeats || Dissecting clinical reasoning
At the Bedside || Explore everyday challenges